AKITA - Best for Clinical Trials
Because of the high efficiency and reproducibility of aerosol deposition, the AKITA is the device of choice in early clinical trials, even if the target device might be different.
A clinical trial involving aerosolized drugs often have to answer the following questions:
- What amount of active agent has to reach the human lungs? In what lung region?
- How can the compliance of the patient be assessed?
- How many patients do I have to include to get a statistically significant result?
The use of the AKITA can help with all questions:
Dose Security and Targeting
By optimizing the flow rate during inspiration, the varaiability of the drug dosage is reduced considerably. This helps to apply a more precise dose, which helps to reduce the number of patients to be recruited.
Besides, the smart card technology allows to target different lung regions by aerosol-bolus technique. Example:
High Drug Amounts
The high efficiency of the AKITA enables to apply high drug amounts within a short time frame, thus reliefing the patients from time-consuming inhalation sessions.
Compliance Data
The AKITA protocols every inhalation treatment onto the smart card with a time stamp. Thus, you can recognize non-compliance in early stages - and react.
Compliance data also be an important support during data interpretation - and by this way give you an important input for your development strategy.